Eustermann S, Schall K, Kostrewa D, Lakomek K, Strauss M, Moldt M and Hopfner K-P. (2018) Structural basis for ATP-dependent chromatin remodelling by the INO80 complex. Nature, 556(7701):386-390. doi: 10.1038/s41586-018-0029-y.

Lakomek K, Stoehr G, Tosi A, Schmailzl M and Hopfner K-P. (2015) Structural basis for dodecameric assembly states and conformational plasticity of the full-length AAA+ ATPases Rvb1○Rvb2. Structure, 23(3):483-495.

Neumann P*, Lakomek K*, Naumann P-T, Erwin WM, Lauhon CT and Ficner R. (2014) Crystal structure of a 4-thiouridine synthetase - RNA complex reveals specificity of tRNA U8 modification. Nucl Acids Res 42(10):6673-6685. (* equal contribution)

Tosi A, Haas C, Herzog F, Gilmozzi A, Berninghausen O, Ungewickell C, Gerhold CB, Lakomek K, Aebersold R, Beckmann R and Hopfner K-P (2013) Structure and subunit topology of the INO80 chromatin remodeler and its interaction with the nucleosome. Cell 154(6), 1207-1219.

Gerhold CB, Winkler DD, Lakomek K, Seifert FU, Fenn S, Kessler B, Witte G, Luger K and Hopfner K-P (2012) Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucl Acids Res 40(21):11036-41106.

Hopfner K-P, Gerhold CB, Lakomek K and Wollmann P (2012) Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines. Curr Opin Struct Biol 22(2), 225-233. (Review)

Lakomek K, Dickmanns A, Ciirdaeva E, Schomacher L and Ficner R (2010) Crystal structure analysis of DNA uridine endonuclease Mth212 bound to DNA. J Mol Biol 399(4), 604-617.

Lakomek K, Dickmanns A, Mueller U, Kollmann K, Deuschl F, Berndt A, Luebke T and Ficner R (2009) De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse. Acta Cryst D65, 220-228.

Lakomek K, Dickmanns A, Kettwig M, Urlaub H, Ficner R and Luebke T (2009) Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC Struct Biol 25, 9:56.

Lakomek K (2009) Structural characterization of the lysosomal 66.3 kDa protein and of the DNA repair enzyme Mth0212 by means of X-ray crystallography. (Dissertation)

Lakomek kristina web

Dr. Kristina Lakomek

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+49 7361 576-442254
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