Prof. Dr. Christian Neusüß

Room

116

Telephone

+49 7361 576-2399

Email Address

Research
Resumé
Publications

The academic study and workplace training; academic knowledge and practical experience; theory and practice of instrumental analytical chemistry and bioanalytics are the main contents of my teaching. These contents are special fields of the masters/master's programme "Analytical and Bioanalytical Chemistry". In addition to advanced courses / specialties in the fundamentals of inorganic, council and physical chemistry, the course focuses on topics in analytics, spectroscopy and biochemistry. As Dean of Studies, Studies Dean of this exciting course, I welcome your interest and will be happy to answer any questions you may have.

In the field (of) research, I am mainly concerned with the coupling of modern separation techniques (CE, LC) with mass spectrometry. As a comparatively rarely practiced School of Engineering, we have built up a great deal of expertise in CE/MS. In addition to fundamental work, this involves a wide range of applications in pharmaceutical analysis, environmental analysis and structure determination. Together with my doctoral candidates, doctoral students and students writing their Masters (UK)/master's (US) thesis or project, we have a lot of fun working in a state-of-the-art laboratory / lab.

Research Projects

Characterization of intact glycoproteins (e.g. EPO) using CE-MS
Method development for the characterization of glycans, based on CE-LIF, CE-MS and LC-MS

Collaboration, cooperation with several (bio)pharmaceutical companies.

Project GEMSE 01.06.2010 - 31.05.201375 KBPDF

The project with the title "Capillary electrophoresis/mass spectrometry - new approach for coupling two important techniques for protein characterization" is funded and supported by the BMBF through the 2010 round of funding for the qualification of young engineers.

Sub-project of MIME 01.11.2011 - 31.10.201469 KBPDF

The sub-project runs under the joint project Multimodal Pattern Recognition System for the Protection of the Population against Organized Drug Crime and for Combating International Drug Trafficking as part of the BMBF's "Securing Commodity Chains" announcement under the Federal Government's "Research for Civil Security" program.

Equipment

Various LC, CE and GC instruments can be coupled with MS, UV, fluorescence, LIF, conductivity detection

Equipment	manufacturer	Variant/Detection
Liquid chromatography*
LC Ultimate 3000	Dionex	LC or capLC
HPLC 1050	Hewlett Packard / Agilen	UV, fluorescence, conductivity detection
HPLC 1100	Agilent	UV, DAD, conductivity detection
HPLC LC-10A VP	Shimadzu	DAD
LC	LDC	Fluorescence (Shimadzu RF-551)

Gas chromatography
GC 5890 Series II Plus	Hewlett Packard / Agilent
GC 5710A	Hewlett Packard / Agilent
GC MCS 5890 Series II	Gerstel
GC-MSD 5890 Series II	Hewlett Packard / Agilent	Quadrupole MS, optional with headspace

Capillary electrophoresis*
CE 7100	Agilent	Optional flexible UV/VIS absorption or LIF at 488nm or 266nm (J+M Analytics)
P/ACE MDQ CE	Beckman Coulter	Optional flexible UV/VIS absorption or LIF at 488nm or 266nm (J+M analytics)
P/ACE System 5500	Beckman Coulter	Optional flexible UV/VIS absorption or LIF at 488nm or 266nm (J+M Analytics)
P/ACE System 5500	Beckman Coulter	Optional flexible UV/VIS absorption or LIF at 488nm or 266nm (J+M Analytics)

Mass spectrometer
Ion trap Esquire 6000	Bruker Daltonics
MicroTOFq-MS	Bruker Daltonics

UV/VIS spectroscopy
UV/VIS spectrometer LKB Ultrospec Plus	Pharmacia

Raman spectroscopy
Raman spectrometer (785nm)	Polytec / J+M Analytics

1989 - today Appointment funding for professors; appointment funds

Jennifer Römer, Alexander Stolz, Steffen Kiessig, Bernd Moritz, Christian Neusüß ISSN: 0731-7085,

Further information

Oliver Höcker, Mike Knierman, Jens Meixner, Christian Neusüß

Further information

Nicolas Drouin, Marlien van Mever, Wei Zhang, Elena Tobolkina, Sabrina Ferre, Anne-Catherine Servais, Marie-Jia Gou, Laurent Nyssen, Marianne Fillet, Guinevere Lageveen-Kammeijer, Jan Nouta, Andrew Chetwynd, Iseult Lynch, James Thorn, Jens Meixner, Christopher Lößner, Myriam Taverna, Sylvie Liu, N. Tran, Yannis Francois, Antony Lechner, Reine Nehmé, Ghassan Al Hamoui Dit Banni, Rouba Nasreddine, Cyril Colas, Herbert Lindner, Klaus Faserl, Christian Neusüß, Manuel Nelke, Stefan Lämmerer, Catherine Perrin, Claudia Bich-Muracciole, Coral Barbas, Ángeles Gonzálvez, Andras Guttman, Marton Szigeti, Philip Britz-McKibbin, Zachary Kroezen, Meera Shanmuganathan, Peter Nemes, Erika Portero, Thomas Hankemeier, Santiago Codesido, Víctor González-Ruiz, Serge Rudaz, Rawi Ramautar

Further information

Alexander Stolz, Ylva Hedeland, Liesa Salzer, Jennifer Römer, Reidun Heiene, Laurent Leclercq, Hervé Cottet, Jonas Bergquist, Christian Neusüß

Further information

Oliver Höcker, Tobias Bader, Torsten Schmidt, Wolfgang Schulz, Christian Neusüß

Further information

Roger Pero-Gascon, Fernando Benavente, Christian Neusüß, Victoria Sanz-Nebot

Further information

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Prof. Dr. Christian Neusüß

Research

Research Projects

Equipment

Resumé

Dean of Studies, Studies Dean "Analytical and Bioanalytical Chemistry"

Professors / Professor of the academic staff for General and Analytical Chemistry

Research assistant/associate/fellow / application chemist at Bruker Daltonik GmbH

Research assistant/associate/fellow at the Department, Institute for Tropospheric Research

Studied chemistry in Heidelberg (German university degree 1996) and Bergen (Norway)

Publications

Online top-down mass spectrometric identification of CE(SDS)-separated antibody fragments by two-dimensional capillary electrophoresis

Two capillary approach for a multifunctional nanoflow sheath liquid interface for capillary electrophoresis-mass spectrometry

Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation

Capillary Zone Electrophoresis-Top-Down Tandem Mass Spectrometry for In-Depth Characterization of Hemoglobin Proteoforms in Clinical and Veterinary Samples

Enrichment-free analysis of anionic micropollutants in the sub-ppb range in drinking water by capillary electrophoresis-high resolution mass spectrometry

Evaluation of on-line solid-phase extraction capillary electrophoresis-mass spectrometry with a nanoliter valve for the analysis of peptide biomarkers